I have a few clients that are having difficulty setting up their outgoing smtp with Outlook and Qwest. With the help of Godaddy support, they helped me make it work for all of my clients. You'll need to know your domain hosting company's incoming and outgoing SMTP servers. You'll need to know your username and password.
Here we go:
I called GoDaddy support. My clients have their sites hosted there, mail through them. I posed this issue and we solved it!
Open Outlook.
Blow off broken account by going under 'tools' >> "account settings"
select the account and click on delete.
Close Outlook - for reasons known only to Microsoft.
Count to 10.
Open Outlook.
OUTLOOK 2007:
Tools - account settings
new account, check the box in the lower left to manually configure it,
Choose pop3 options
Type in your name you want the mail to be from when people receive it.
type in full email address for account, pop3,
in - pop.secureserver.net,
out - smtpout.secureserver.net
username is the full email address.
password - hopefully you know this.
Don't check the box in lower left.
Click on, "More settings."
outgoing server tab:
select, "my outgoing server requires authentication."
select, "use same settings as incoming."
connect tab - default (LAN for me)
advanced tab:
check the box: this server requires an encrypted connection (SSL).
incoming will default now to 995.
outgoing smtp port - 465
encrypted connection - GoDaddy had me choose SSL.
OK, next, finish.
send email.
Testing with myQwest subscriber client - worked BEAUTIFULLY!
I hope this helped you!

Comments